Title of article
Alkylbenzyl ethers of hydroquinones as monoamine oxidase B inhibitors
Author/Authors
Argyrios G. Arvanitis، نويسنده , , Everett L. Scholfield، نويسنده , , Dimitri Grigoriadis، نويسنده , , Peter G. Heytler، نويسنده , , Jack Bowdle، نويسنده , , Robert J. Chorvat، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
115
To page
120
Abstract
A series of alkylbenzylethers of substituted hydroquinone analogs of 4-(3-chlorophenyl methyloxy)-phenoxybutyronitrile I, and alcohol II were synthesized as monoamine oxidase (MAO) inhibitors. Incorporation of electron-withdrawing groups on the hydroquinone afforded compounds with higher levels of activity and selectivity than I or II for MAO B inhibition.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787868
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