Title of article
Synthesis and pharmacology of 2-alkyl raloxifene analogs
Author/Authors
Timothy A. Grese، نويسنده , , Stephen Cho، نويسنده , , Henry U. Bryant، نويسنده , , Harlan W. Cole، نويسنده , , Andrew L. Glasebrook، نويسنده , , David E. Magee، نويسنده , , D. Lynn Phillips، نويسنده , , Ellen R. Rowley، نويسنده , , Lorri L. Short، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
201
To page
206
Abstract
A series of 2-alkyl and 2-cycloalkyl raloxifene analogs have been prepared and evaluated in both in vitro and in vivo models of estrogen/antiestrogen activity. In particular, the 2-cyclohexyl analogs show promise as potent selective estrogen-receptor modulators (SERMs).
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787885
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