Author/Authors :
D. Fancelli، نويسنده , , C. Caccia، نويسنده , , M. G. Fornaretto، نويسنده , , R. McArthur، نويسنده , , D. Severino، نويسنده , , F. Vaghi، نويسنده , , M. Varasi، نويسنده ,
Abstract :
Structure-activity relationships in a series of dihydrobenzofuran derivatives related structurally to the 5-HT3 antagonist and 5-HT4 agonist ADR 932 (1) were investigated. Members of this series, such as (18) and (23), were found to be 5-HT4 agonists or partial agonists endowed with remarkably high affinity and selectivity.