Title of article
First synthesis of enantiomerically pure carbocyclic oxanosine as a potential chemotherapeutic agent
Author/Authors
Hiroko Kurata، نويسنده , , Shigeru Nishiyama، نويسنده , , Shosuke Yamamura، نويسنده , , Kuniki Kato، نويسنده , , Sari Fujiwara and، نويسنده , , Kazuo Umezawa، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
4
From page
283
To page
286
Abstract
The first synthesis of optically active carbocyclic oxanosine 2 has been achieved in 14 steps from commercially available -ribonic acid γ-lactone. When evaluated for the inhibition activity of NGF-induced differentiation on PC12 cells, 2 was about 10-fold less active than natural oxanosine.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787901
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