Author/Authors :
Hiroko Kurata، نويسنده , , Shigeru Nishiyama، نويسنده , , Shosuke Yamamura، نويسنده , , Kuniki Kato، نويسنده , , Sari Fujiwara and، نويسنده , , Kazuo Umezawa، نويسنده ,
Abstract :
The first synthesis of optically active carbocyclic oxanosine 2 has been achieved in 14 steps from commercially available -ribonic acid γ-lactone. When evaluated for the inhibition activity of NGF-induced differentiation on PC12 cells, 2 was about 10-fold less active than natural oxanosine.
