Title of article
Design, synthesis and X-ray crystallographic studies of [7.3.1] and [8.3.1] macrocyclic FKBP-12 ligands
Author/Authors
Robert E. Babine، نويسنده , , T. M. Bleckman، نويسنده , , Ethel S. Littlefield، نويسنده , , Hans E. Parge، نويسنده , , L. A. K. Pelletier، نويسنده , , Cristina T. Lewis، نويسنده , , Judy V. French، نويسنده , , Michael Imbacuan، نويسنده , , Susumo Katoh، نويسنده , , John H. Tatlock، نويسنده , , Richard E. Showalter، نويسنده , , J. Ernest Villafranca، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
385
To page
390
Abstract
The design, synthesis, and structure activity relationships of a series of novel macrocyclic FKBP-12 ligands 1 are reported. The crystal structure of the complex between 7 and human FKBP-12 is reported and some SAR results are discussed based on this complex.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787922
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