Author/Authors :
John L. Gilmore، نويسنده , , Sheryl J. Hays، نويسنده , , Bradley W. Caprathe، نويسنده , , Chitase Lee، نويسنده , , Mark R. Emmerling، نويسنده , , Walter Michael Halbmayer، نويسنده , , Juan C. Jaen، نويسنده ,
Abstract :
A series of 2-aryl-4H-3,1-benzoxazin-4-ones have been synthesized and tested for inhibitory activity against C1r serine protease. Compounds were found that were equipotent and more selective than the reference compound FUT-175.
