• Title of article

    The design and synthesis of novel adenosine agonists

  • Author/Authors

    P. J. Scammells، نويسنده , , S. P. Baker، نويسنده , , L. Bellardinelli، نويسنده , , R. A. Olsson، نويسنده , , R. A. Russell، نويسنده , , S. A. Knevitt، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1996
  • Pages
    4
  • From page
    811
  • To page
    814
  • Abstract
    The 2R and 2S-endo isomers of N6-(5,6-epoxynorborn-2-yl)adenosine have been synthesised and shown to be potent agonists for the A1 adenosine receptor. The 2S-endo isomer was equipotent to N6-cyclopentyladenosine and 10- to 12-fold more potent than the 2R-endo isomer.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1996
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    788006