Title of article
Synthesis and in vitro cytotoxicity of (RS)-20-desethyl-20-substituted camptothecin analogues
Author/Authors
Sang-sup Jew، نويسنده , , Myoung Goo Kim، نويسنده , , Hee-Jin Kim، نويسنده , , Eun-Young Roh، نويسنده , , Youn-sang Cho، نويسنده , , Joon-Kyum Kim، نويسنده , , Kyung-Hoe Cha، نويسنده , , Kang-Keun Lee، نويسنده , , Hyun-Jung Han، نويسنده , , Heesoon Lee، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
4
From page
849
To page
852
Abstract
Sixteen (RS)-20-desethyl-20-substituted camptothecin analogues were designed and prepared by total synthesis. These analogues were evaluated for cytotoxic activity against five tumor cell lines. The cytotoxic activity of compound 14f was shown to be comparable to that of camptothecin.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788014
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