Title of article :
Synthesis and in vitro cytotoxicity of (RS)-20-desethyl-20-substituted camptothecin analogues
Author/Authors :
Sang-sup Jew، نويسنده , , Myoung Goo Kim، نويسنده , , Hee-Jin Kim، نويسنده , , Eun-Young Roh، نويسنده , , Youn-sang Cho، نويسنده , , Joon-Kyum Kim، نويسنده , , Kyung-Hoe Cha، نويسنده , , Kang-Keun Lee، نويسنده , , Hyun-Jung Han، نويسنده , , Heesoon Lee، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1996
Pages :
4
From page :
849
To page :
852
Abstract :
Sixteen (RS)-20-desethyl-20-substituted camptothecin analogues were designed and prepared by total synthesis. These analogues were evaluated for cytotoxic activity against five tumor cell lines. The cytotoxic activity of compound 14f was shown to be comparable to that of camptothecin.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
1996
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
788014
Link To Document :
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