Title of article
Synthesis and biological evaluation of flavonoids and related compounds as gastroprotective agents
Author/Authors
Jeffrey J. Ares، نويسنده , , Pamela E. Outt، نويسنده , , Jared L. Randall، نويسنده , , Jeffrey N. Johnston، نويسنده , , Peter D. Murray، نويسنده , , Linda M. OʹBrien، نويسنده , , Pamela S. Weisshaar، نويسنده , , Beth L. Ems، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
4
From page
995
To page
998
Abstract
Several analogs of the gastroprotective molecule flavone have been synthesized and evaluated for gastroprotective activity. A C2–C3 double bond and an intact C ring appear necessary for optimum activity. Activity can be retained by replacing the 2-phenyl substituent with other groups but is eliminated when this ring is moved from the 2- to the 3-position.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788046
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