Title of article
Inhibition of protein phosphatase 2A by cantharidin analogues
Author/Authors
Adam McCluskey، نويسنده , , Cherie Taylor، نويسنده , , Ronald J. Quinn، نويسنده , , Masami Suganuma، نويسنده , , Hirota Fujiki، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
4
From page
1025
To page
1028
Abstract
The syntheses of several cantharidin analogues and their biochemical effects on protein phosphatase 2A are described. Comparison of the PP2A inhibition of these cantharidin analogues has shown that the 7-oxo moiety and the anhydride system contribute to the biochemical activity. The diacid forms of several anhydrides showed reduced inhibition of PP2A.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788052
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