• Title of article

    Design, synthesis, and antitumor activity of bicyclic and isomeric analogues of illudin M

  • Author/Authors

    Frederick R. Kinder Jr.، نويسنده , , Run-Ming Wang، نويسنده , , William E. Bauta، نويسنده , , Kenneth W. Bair، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1996
  • Pages
    6
  • From page
    1029
  • To page
    1034
  • Abstract
    Novel bicyclic and isomeric analogues of the cytotoxic sesquiterpine illudin M were prepared using 1,3-dipolar cycloaddition reactions. Nearly every analogue investigated demonstrated low μM IC50 values when tested in a panel of four human tumor cell lines.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1996
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    788053