Title of article
DNA cleavage of novel propargylic sulfones. Enhancement of potency via intercalating interaction
Author/Authors
Wei-Min Dai، نويسنده , , Kin Chiu Fong، نويسنده , , Hiroshi Danjo، نويسنده , , Sei-ichi Nishimoto، نويسنده , , Michael Solow، نويسنده , , Wing Leung Mak، نويسنده , , Mau Lam Yeung، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
1093
To page
1098
Abstract
A number of novel hydroxy propargylic sulfones 7–15 were synthesized as DNA cleaving agents. Enhancement of DNA cleavage potency was observed with those compounds which could interact with DNA through intercalation of the extended aromatic rings.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788066
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