Title of article :
DNA cleavage of novel propargylic sulfones. Enhancement of potency via intercalating interaction
Author/Authors :
Wei-Min Dai، نويسنده , , Kin Chiu Fong، نويسنده , , Hiroshi Danjo، نويسنده , , Sei-ichi Nishimoto، نويسنده , , Michael Solow، نويسنده , , Wing Leung Mak، نويسنده , , Mau Lam Yeung، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1996
Pages :
6
From page :
1093
To page :
1098
Abstract :
A number of novel hydroxy propargylic sulfones 7–15 were synthesized as DNA cleaving agents. Enhancement of DNA cleavage potency was observed with those compounds which could interact with DNA through intercalation of the extended aromatic rings.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
1996
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
788066
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=788066
