Title of article
A topliss tree analysis of the HIV-protease inhibitory activity of 6-phenyl-4-hydroxy-pyran-2-ones
Author/Authors
Bruce A. Steinbaugh، نويسنده , , Harriet W. Hamilton، نويسنده , , J. V. N. Vara Prasad، نويسنده , , Kimberly S. Para، نويسنده , , Tummino Peter J.، نويسنده , , Donna Ferguson، نويسنده , , Elizabeth A. Lunney، نويسنده , , C. John Blankley، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
1099
To page
1104
Abstract
In a study of 4-hydroxy-pyran-2-ones as possible inhibitors of HIV protease, a series of compounds were synthesized following the Topliss operational scheme for substitution on a phenyl group at the 6 position of the pyrone. In addition, a number of compounds with polar substituents were made.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788067
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