Title of article
Anti-human immunodeficiency virus activity and cytotoxicity of derivatized buckminsterfullerenes
Author/Authors
David I. Schuster، نويسنده , , Stephen R. Wilson، نويسنده , , Raymond F. Schinazi، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
4
From page
1253
To page
1256
Abstract
Eleven new functional derivatives of C60 have been tested for anti-HIV activity in peripheral blood mononuclear cells infected with HIV-1LAV. Nine compounds displayed activity in the low micromolar range (EC50), three of them lower than any fullerene derivative reported to date. With one exception, these compounds displayed no cytotoxicity up to 100 μM.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788097
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