Title of article
Synthesis of (3R)- and (3S)-Fluoro-(4R,5R)-dihydroxy-1-cyclohexene-1-carboxylic acids: The (3R)- and (3S)-fluoro analogues of (−)-shikimic acid
Author/Authors
Roger Brettle، نويسنده , , Richard Cross، نويسنده , , Martyn Frederickson، نويسنده , , Edwin Haslam، نويسنده , , Fiona S. MacBeath، نويسنده , , Gareth M. Davies، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
4
From page
1275
To page
1278
Abstract
(3R)- and (3S)-Fluoro-(4R,5R)-dihydroxy-1-cyclohexene-1-carboxylic acids (the (3R)- and (3S)-fluoro analogues of (−)-shikimic acid) have been synthesised from (−)-shikimic acid via an intermediate epoxide (a fungal metabolite from Chalara microspora) that underwent acid catalysed hydrolysis to afford the first stereospecific synthesis of (−)-3-epi-shikimic acid.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788102
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