Author/Authors :
Yoshio Hayashi، نويسنده , , Yoshimi Sato، نويسنده , , Jun Katada، نويسنده , , Yoshimi Takiguchi، نويسنده , , Iwao Ojima، نويسنده , , Isao Uno، نويسنده ,
Abstract :
The structure-activity relationships of N-terminal modified RGD peptides against platelet aggregation inhibitory activity were studied, and Orotyl-Ser-Arg-Gly-Asp-Trp (NSL-9403) was found to be a new and effective anti-thrombotic agent during extracorporeal circulation.