• Title of article

    4-bromo-1-methoxy-N-[2-(4-aryl-1-piperazinyl)ethyl]-2-naphthalenecarboxamides: Selective dopamine D3 receptor partial agonists

  • Author/Authors

    Shelly A. Glase، نويسنده , , Hyacinth C. Akunne، نويسنده , , Thomas G. Heffner، نويسنده , , Stephen J. Johnson، نويسنده , , Suzanne R. Kesten، نويسنده , , Robert G. MacKenzie، نويسنده , , Peter J. Manley، نويسنده , , Thomas A. Pugsley، نويسنده , , Jon L. Wright، نويسنده , , Lawrence D. Wise، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1996
  • Pages
    6
  • From page
    1361
  • To page
    1366
  • Abstract
    A series of 4-bromo-1-methoxy-N-[2-(4-aryl-1-piperazinyl)ethyl]-2-naphthalenecarboxamide dopamine (DA) D3 receptor agonists has been identified. These compounds were found to be selective for DA D3 over D2 receptors and were shown to be partial to full agonists as measured by stimulation of mitogenesis in D3-transfected CHO p-5 cells.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1996
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    788119