Author/Authors :
Shelly A. Glase، نويسنده , , Hyacinth C. Akunne، نويسنده , , Thomas G. Heffner، نويسنده , , Stephen J. Johnson، نويسنده , , Suzanne R. Kesten، نويسنده , , Robert G. MacKenzie، نويسنده , , Peter J. Manley، نويسنده , , Thomas A. Pugsley، نويسنده , , Jon L. Wright، نويسنده , , Lawrence D. Wise، نويسنده ,
Abstract :
A series of 4-bromo-1-methoxy-N-[2-(4-aryl-1-piperazinyl)ethyl]-2-naphthalenecarboxamide dopamine (DA) D3 receptor agonists has been identified. These compounds were found to be selective for DA D3 over D2 receptors and were shown to be partial to full agonists as measured by stimulation of mitogenesis in D3-transfected CHO p-5 cells.
