Title of article
A new linker for primary amines applicable to combinatorial approaches
Author/Authors
Willi Bannwarth، نويسنده , , Josef Huebscher، نويسنده , , Richard Barner، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
4
From page
1525
To page
1528
Abstract
We describe a new linker molecule (ADCC-linker) for the attachment of primary amines to solid support. The linker is stable towards acidic conditions (eg.TFA) basic conditions (eg.piperidine, DBU) as well as towards uronium type coupling reagents. The amine can be quantitatively released from the support using a 2 % hydrazine in DMF solution.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788152
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