Title of article
Synthesis and technetium-99m labeling of cyclic GP IIb/IIIa receptor antagonists conjugated to 4,5-bis(mercaptoacetamido)-pentanoic acid (mapt)
Author/Authors
Milind Rajopadhye، نويسنده , , D. Scott Edwards، نويسنده , , Jeffrey P. Bourque، نويسنده , , Timothy R. Carroll، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
4
From page
1737
To page
1740
Abstract
The synthesis of cyclic Arg-Gly-Asp GP IIb/IIIa receptor antagonists conjugated to 4,5-bis(S-1-ethoxyethyl-mercaptoacetamido)pentanoic acid is reported. The corresponding Tc-99m-labeled complexes were prepared by exchange labeling with Tc-99m-glucoheptonate. This indirect labeling approach is an alternative to the preformed chelate approach using mapt.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788193
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