Title of article
Synthesis of C-oxetanosyl-thiazole and its carbocyclic analog nucleosides as potential chemotherapeutic agents
Author/Authors
Yoshiko Kikuchi، نويسنده , , Shigeru Nishiyama، نويسنده , , Shosuke Yamamura، نويسنده , , Kuniki Kato، نويسنده , , Sari Fujiwara and، نويسنده , , Kazuo Umezawa، نويسنده , , Yukimasa Terada، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
4
From page
1897
To page
1900
Abstract
Novel C-nucleosides (2′S, 3′S)-2-[2′, 3′-(bishydroxymethyl)-oxetan-1′-yl]-1,3-thiazole-4-carboxamide3 and its carbocyclic analog 4 have been synthesized. Compound 4 enhanced NGF-induced differentiation on PC12 cells at 100 μg/ml, and moreover, 4 alone also induced morphological differentiation significantly at 10 and 100 μg/ml.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788223
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