Title of article
Thiono triester modified antisense oligonucleotides for inhibition of human cytomegalovirus in vitro
Author/Authors
Zhaoda Zhang، نويسنده , , Jean A. Smith، نويسنده , , Adrienne P. Smyth، نويسنده , , Warren Eisenberg، نويسنده , , Gregory S. Pari، نويسنده , , Jin Yan Tang، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
1911
To page
1916
Abstract
A series of thiono triester containing oligonucleotide phosphorothioates linked with a lipophilic group have been successfully synthesized. Some of these modified antisense oligonucleotides show potent anti-HCMV activity as well as improved cellular association and nuclease resistance.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788226
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