Author/Authors :
Daniele Andreotti، نويسنده , , Stefano Biondi، نويسنده , , Romano Di Fabio، نويسنده , , Daniele Donati، نويسنده , , Elisabetta Piga، نويسنده , , Tino Rossi، نويسنده ,
Abstract :
Synthesis of new 4-alkoxy substituted trinems 4, 5, 6, 7 and 8 together with their antibacterial profiles compared to imipenem and GV104326 (2) are described. The good antibacterial profile observed for derivatives 4–7 encouraged further exploration of these derivatives.