Title of article :
The first selective antagonist for a GABAC receptor
Author/Authors :
Yoshinori Murata، نويسنده , , Richard M. Woodward، نويسنده , , Ricardo Miledi، نويسنده , , Larry E. Overman، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1996
Abstract :
(1,2,5,6-Tetrahydropyridine-4-yl)methylphosphinic acid (TPMPA, 1), which is synthesized in six steps from 3-butyn-1-ol, is the first γ-aminobutyric acid (GABA) receptor antagonist that shows strong selectivity for mammalian GABAC receptors.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters