Author/Authors :
Myoung Goo Kim، نويسنده , , Jae Chul Jung، نويسنده , , Moo Je Sung، نويسنده , , Young Key Choi، نويسنده , , Sang Geun Hahn، نويسنده , , Se-Jong Lee، نويسنده , , Geal-Jung Yoon، نويسنده , , Myung Hwan Park، نويسنده ,
Abstract :
The synthesis and in vitro activity of cephalosporins with hydroxamic acid at the 7-position are described. Anti-pseudomonal activity of the compound 11a was shown to be comparable to that of ceftazidime. Especially, the compound 11a exhibited good activity against Gram-positive bacteria including Streptococcus pneumoniae and Staphylococcus aureus.
