Author/Authors :
Tien L. Huang، نويسنده , , Qian Zhang، نويسنده , , Angele T. White، نويسنده , , Sherry F. Queener، نويسنده , , Marilyn S. Bartlett، نويسنده , , James W. Smith، نويسنده , , Isaac O. Donkor، نويسنده ,
Abstract :
A series of novel piperidine-linked aromatic diimidazolines (3–7) have been synthesized as conformationally restricted congeners of the anti-Pneumocystis carinii drug, Pentamidine. These compounds significantly inhibited the growth of Pneumocystis carinii in culture at 1 μg/mL.
