Title of article
Tetrahydrothienopyridine derivatives as novel GPIIb/IIIa antagonists
Author/Authors
Kiyoaki Katano، نويسنده , , Eiki Shitara، نويسنده , , Masaro Shimizu، نويسنده , , KAZUE SASAKI، نويسنده , , Tomoaki Miura، نويسنده , , Yasuko Isomura، نويسنده , , Mami Kawaguchi، نويسنده , , Shokichi Ohuchi، نويسنده , , Takashi Tsuruoka، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
2601
To page
2606
Abstract
The tetrahydrothienopyridine derivatives were derived from aminomethylcyclohexylcarboxylic acid as a lead moiety. Evaluation of the antiplatelet activity and receptor binding assay revealed that compound 1(ME3277) was a novel and potent non-peptide and non-amidinophenyl GPIIb/IIIa antagonist.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788402
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