Author/Authors :
Yoshihiro Mimaki، نويسنده , , Minpei Kuroda، نويسنده , , Aiko Kameyama، نويسنده , , Yutaka Sashida، نويسنده , , Toshihiko Hirano، نويسنده , , Kitaro Oka، نويسنده , , Akira Dobashi، نويسنده , , Kazuo Koike، نويسنده , , Tamotsu Nikaido، نويسنده ,
Abstract :
A new rearranged cholestane glycoside (1) was isolated from Ornithogalum saundersiae bulbs by monitoring the cytostatic activity on leukemia HL-60 cells. Compound 1 was exceptionally cytostatic against HL-60 and MOLT-4 cells, which was revealed to be mediated partially through induction of apoptosis.