Author/Authors :
Ryoji Hirose، نويسنده , , Norimitsu Hamamichi، نويسنده , , Yuuki Kitao، نويسنده , , Tohru Matsuzaki، نويسنده , , Kenji Chiba، نويسنده , , Tetsuro Fujita، نويسنده ,
Abstract :
The 2-aminoalcohol series of immunosuppressants showed a bell-shaped relationship between the activity and the carbon number. The (R)-isomers were more potent than the (S)-isomers, and (R)-2-aminohexadecanol displayed comparably activity to a potent immunosuppressant, FTY720.