Title of article
Thiophenesulfonamides as endothelin receptor antagonists
Author/Authors
C. B. Raju ، نويسنده , , Chengde Wu، نويسنده , , Adam Kois، نويسنده , , Erik Verner، نويسنده , , Ilya Okun، نويسنده , , Fiona Stavros، نويسنده , , Ming Fai Chan، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
2651
To page
2656
Abstract
The synthesis and in vitro binding affinities of a series of thiophenesulfonamides as ETA selective endothelin receptor antagonists is described. The most potent inhibitor displayed an IC50 of 43 nM and 3 μM to ETA and ETB receptors, respectively.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788412
Link To Document