Author/Authors :
Dharmpal S. Dodd، نويسنده , , Zhongqi Shen، نويسنده , , Takao Nishi MD، نويسنده , , Norma Graber، نويسنده , , Dawson Bealls، نويسنده , , Miranda Fong، نويسنده , , Tracy Ebert، نويسنده ,
Abstract :
2-Alkylsulfinyl-1,3,4-oxadiazoles have been identified as novel inhibitors of cell adhesion molecule expression on endothelial cells. These compounds have been shown to inhibit the up-regulation of ELAM-1 and VCAM-1 on activated human umbilical vein endothelial cells (HUVECs) as measured by ELISA.