Title of article
Synthesis and biological evaluation of novel 2-vinyl carbapenems. Remarkable DHP-1 stability of 1′-substituted analogs
Author/Authors
Akira Yamada، نويسنده , , Kouji Hattori، نويسنده , , Satoru Kuroda، نويسنده , , Toshiyuki Chiba، نويسنده , , Toshiaki Kamimura، نويسنده , , Kazuo Sakane، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
4
From page
2705
To page
2708
Abstract
The synthesis antibacterial activity and DHP-susceptibility of a series of novel 2-vinyl carbapenems is described. Carbapenems having a 1′-substituted vinyl moiety at the 2 position were found to be very stable toward DHP-1, displaying comparable stability to compounds with a 1β-methyl functionality.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788422
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