Title of article
Enzymatic synthesis and antiviral ativity of 2′-deoxy-2′-fluoro-ribavirin
Author/Authors
Martin J. Slater، نويسنده , , Clare Gowrie، نويسنده , , G.A. Freeman، نويسنده , , S.A. Short، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
4
From page
2787
To page
2790
Abstract
2′-Deoxy-2′-fluoro-ribavirin has been efficiently synthesised from 2′-deoxy-2′-fluorouridine using nucleoside transferase as the key step, and evaluated for its antiviral properties in cell culture. An efficient synthesis of 3,5-di-O-p-chlorobenzoyl-2-deoxy-2-fluoro-β-D-ribofuranose is also described.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788440
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