Title of article
Synthesis of novel ellipticine analogues and their inhibition of Moloney leukaemia reverse transcriptase
Author/Authors
Géza Tim?ri، نويسنده , , Tibor So?s، نويسنده , , Gyorgy Hajos، نويسنده , , Andr?s Messmer، نويسنده , , J?nos Nacsa، نويسنده , , Jozsef Molnar، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
2831
To page
2836
Abstract
Two new ellipticine analogues were synthetized as potential non nucleoside inhibitors of reverse transcriptase and were tested on Moloney leukaemia virus reverse transcriptase in vitro. Both derivatives (9a,b) showed considerable inhibitory effect; ID50 was found to be in the range of 2.8 to 4.5 × 10−5 M.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788449
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