Title of article
Synthesis and structure-activity relationships of 9-substituted acridines as endothelin-A receptor antagonists
Author/Authors
X. -M. Cheng، نويسنده , , C. Lee، نويسنده , , S. Klutchko، نويسنده , , T. Winters، نويسنده , , E. E. Reynolds، نويسنده , , K. M. Welch، نويسنده , , M. A. Flynn، نويسنده , , A. M. Doherty، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
4
From page
2999
To page
3002
Abstract
Screening of a compound library against endothelin receptors (ETA and ETB) revealed PD 102566 (compound 1) as an ETA selective antagonist. Synthesis and structure-activity relationships (SAR) of a series of analogs are described.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788484
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