Title of article
Benzolactam growth hormone secretagogues: Replacement of the C-3 amide bond in L-692,429
Author/Authors
Hyun O. Ok، نويسنده , , John L. Szumiloski، نويسنده , , George A. Doldouras، نويسنده , , William R. Schoen، نويسنده , , Kang Cheng، نويسنده , , Wanda W. -S. Chan، نويسنده , , Bridget S. Butler، نويسنده , , Roy G. Smith، نويسنده , , Michael H. Fisher، نويسنده , , Matthew J. Wyvratt Jr.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
3051
To page
3056
Abstract
The synthesis and structure-activity relationships of various C-3 amide bond modifications in the novel nonpeptidyl growth hormone secretagogue L-692,429 are described. Several C-3 amide surrogates were prepared and the urea moiety was found to exhibit growth hormone releasing activity similar to that observed with L-692,429.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788496
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