Title of article
The synthesis and biological activity of some known and putative metabolites of the atypical antipsychotic agent olanzapine (LY170053)
Author/Authors
David O. Calligaro، نويسنده , , John Fairhurst، نويسنده , , Terrence M. Hotten، نويسنده , , Nicholas A. Moore، نويسنده , , David E. Tupper، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
6
From page
25
To page
30
Abstract
4′-N-desmethyl olanzapine (2), olanzapine 4′-N-oxide (3) and 2-hydroxymethyl olanzapine (5), have been prepared and their pharmacology compared to that of the parent compound olanzapine (1). The 4′-N-quaternary glucuronide (8) has also been prepared.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1997
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788502
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