Title of article
Cytotoxicity and actin depolymerizing activity of aplyronine A, a potent antitumor macrolide of marine origin, and the natural and artificial analogs
Author/Authors
Kiyotake Suenaga، نويسنده , , Noriyuki Kamei، نويسنده , , Youko Okugawa، نويسنده , , Masaki Takagi، نويسنده , , Atsushi Akao، نويسنده , , Hideo Kigoshi، نويسنده , , Kiyoyuki Yamada، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
6
From page
269
To page
274
Abstract
The artificial analogs of aplyronine A (1), a potent cytotoxic and antitumor macrolide, were synthesized and the structure-activity (cytotoxicity and actin depolymerizing activity) studies were performed; the side chain portion in 1 was found to play a key role in both biological activities.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1997
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788552
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