• Title of article

    Studies on the active conformation of NK1 antagonist CGP 49823. Part 1. Synthesis of conformationally restricted analogs.

  • Author/Authors

    Siem J. Veenstra، نويسنده , , Kathleen Hauser، نويسنده , , Claudia Betschart، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1997
  • Pages
    4
  • From page
    347
  • To page
    350
  • Abstract
    Five conformationally restricted analogs of CGP 49823 have been synthesized. Comparison of their in vitro activities indicates an active conformation of CGP 49823 in which the two aromatic rings of the benzyl and the benzoyl groups are in proximity of each other.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1997
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    788566

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=788566