• Title of article

    3-Amino-1,2-benzisoxazoles: A new family of potent inhibitors of LTB4 binding to the human neutrophils

  • Author/Authors

    Hongsuk Suh، نويسنده , , Soo-Jeong Jeong، نويسنده , , Yong Nam Han، نويسنده , , Hwa-Jin Lee، نويسنده , , Jae-Ha Ryu، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1997
  • Pages
    4
  • From page
    389
  • To page
    392
  • Abstract
    A new family of 3-amino-1,2-benzisoxazoles was designed and synthesized to be a potent inhibitors of LTB4 binding to the human neutrophils. HS-1141 appears to be one of the strongest inhibitors of LTB4 binding reported so far (IC50=7nM).
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1997
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    788575