Title of article
Conversion of acyclic nonpeptide CCK antagonists into CCK agonists
Author/Authors
Gavin C. Hirst، نويسنده , , Kennedy L. Queen، نويسنده , , Elizabeth F. Sugg، نويسنده , , Timothy M. Willson and Shawn P. Williams، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
4
From page
511
To page
514
Abstract
The CCK antagonists RP 69758 and (R)-lorglumide were converted into CCK agonists by the introduction of an N-isopropylanilide agonist “trigger.” The common structural features of these ligands suggest that nonpeptide agonists and antagonists bind to a common site in the CCK receptor.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1997
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788600
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