Title of article
Molecular connectivity to find β-blockers with low toxicity
Author/Authors
R. Garc?a-Domenech، نويسنده , , C. de Gregorio Alapont، نويسنده , , J. V. de Juli?n-Ortiz، نويسنده , , J. G?lvez، نويسنده , , L. Popa، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
6
From page
567
To page
572
Abstract
Molecular connectivity has been used to find new β-blocker drugs using linear discriminant analysis and connectivity functions with different topological descriptors. Among the selected compounds stands out the probucol and the β-carotene. Both of them interact with β adrenoceptors.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1997
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788610
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