• Title of article

    Vasopressin trisulphide: synthesis, NMR study and affinity studies with V1 and V2 subtypes receptors

  • Author/Authors

    Mireille Moutiez، نويسنده , , Guy Lippens، نويسنده , , Christian Sergheraert، نويسنده , , André Tartar، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1997
  • Pages
    6
  • From page
    719
  • To page
    724
  • Abstract
    A trisulfide-containing analogue of [arginine8]-vasopressin has been synthesized from the corresponding dithiol derivative. Affinities for V1 and V2 receptors were determined. Characterization of the structural differences with the parent hormone was achieved by NMR analysis and a model was built from the disulphide derivative.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1997
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    788640