Author/Authors :
Christopher Blackburn، نويسنده , , Aruna Pingali، نويسنده , , Terry Kehoe، نويسنده , , Lee W. Herman، نويسنده , , Hongqi Wang، نويسنده , , Steven A. Kates، نويسنده ,
Abstract :
Libraries of ACE inhibitors were prepared by solid-phase methods involving reductive alkylation of resin-bound dipeptides, H-X-Pro-DHPP-PEG-PS or H-X-X-PAL-PEG-PS. Affinity selection of the library components identified hydrophilic N-alkylated dipeptides as potential inhibitors.
