• Title of article

    Libraries of angiotensin converting enzyme inhibitors: Solid-phase synthesis and affinity selection

  • Author/Authors

    Christopher Blackburn، نويسنده , , Aruna Pingali، نويسنده , , Terry Kehoe، نويسنده , , Lee W. Herman، نويسنده , , Hongqi Wang، نويسنده , , Steven A. Kates، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1997
  • Pages
    4
  • From page
    823
  • To page
    826
  • Abstract
    Libraries of ACE inhibitors were prepared by solid-phase methods involving reductive alkylation of resin-bound dipeptides, H-X-Pro-DHPP-PEG-PS or H-X-X-PAL-PEG-PS. Affinity selection of the library components identified hydrophilic N-alkylated dipeptides as potential inhibitors.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1997
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    788659