Title of article :
Synthesis and biological evaluation of 1α-hydroxy-25(R and S)-25,26-Epoxy-23-yne vitamin D3 and of 1α,25(R and S),26-Trihydroxy-23-yne vitamin D3
Author/Authors :
Yusheng Wu، نويسنده , , Xu-yang Zhao، نويسنده , , P. De Clercq، نويسنده , , M. Vandewalle، نويسنده , , R. Bouillon، نويسنده , , A. Verstuyf، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1997
Abstract :
The synthesis of both 1α-hydroxy-25(R and S)-25,26-epoxy-23-yne vitamin D3 and of both 1α,25(R and S),26-trihydroxy-23-yne vitamin D3 is described. Biological evaluation includes the study of calcemic effect, receptor binding and cell differentiation.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
