• Title of article

    Bioactivatable derivatives of 8-substituted cAMP-analogues

  • Author/Authors

    Jens Kruppa، نويسنده , , Stephen Keely، نويسنده , , Frank Schwede، نويسنده , , Carsten Schultz، نويسنده , , Kim E. Barrett، نويسنده , , Bernd Jastorff، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1997
  • Pages
    4
  • From page
    945
  • To page
    948
  • Abstract
    Four 8-substituted derivatives of cAMP were converted into their membrane-permeant acetoxymethyl esters (AM-esters). The activity of these bioactivatable compounds to induce chloride secretion of T84 cells was up to 100-fold increased compared to the non-modified cAMP derivatives.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1997
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    788683