Title of article
Benzo[c]quinoliziniums: A new family of inhibitors for protein kinase CK II
Author/Authors
Y. Mettey، نويسنده , , J-M. Vierfond، نويسنده , , M. Baudry، نويسنده , , C. Cochet and، نويسنده , , D. Sarrouilhe، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
4
From page
961
To page
964
Abstract
A series of bicyclic enols 3 and tricyclic benzo[c]quinoliziniums 4 and 5 were prepared and evaluated as inhibitors of protein kinase CKII. Of the seventeen derivatives examined, 6-hydroxy-benzo[c]quinolizinium5d was the most potent inhibitor and exhibited a good selectivity for CKII in the micromolar range.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1997
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788686
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