• Title of article

    Synthesis and binding affinity of new muscarinic ligands structurally related to oxotremorine

  • Author/Authors

    Paola Conti، نويسنده , , Clelia Dallanoce، نويسنده , , Marco De Amici، نويسنده , , Carlo De Micheli، نويسنده , , Bjarke Ebert، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1997
  • Pages
    4
  • From page
    1033
  • To page
    1036
  • Abstract
    The synthesis and radioligand binding assays of a group of muscarinic ligands related to oxotremorine are reported. The new compounds displayed binding affinities comparable to those of the parent molecule with the exception of the trimethylammonium salt 6, which behaved as a full muscarinic agonist and showed a pronounced selectivity for M2 versus M1 muscarinic receptor subtypes
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1997
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    788702

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=788702