Title of article :
A CHROMOGENIC SUBSTRATE FOR THE CONTINUOUS ASSAY OF MAMMALIAN PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C
Author/Authors :
Aleksey V. Rukavishnikov، نويسنده , , Margret Ryan، نويسنده , , O. Hayes Griffith، نويسنده , , John F. W. Keana، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1997
Abstract :
The synthesis of a chromogenic substrate for mammalian PI-PLC, -myo-inositol 4,5-bis(dihydrogen phosphate) 1-(4-nitrophenyl hydrogen phosphate) tetrasodium salt (13), is described. Phosphoinositol bisphosphate 13 (NPIP-P2) is shown to be a substrate for human PI-PLCδ1 in a non-radioactive, continuous assay. © 1997 Elsevier Science Ltd.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
