• Title of article

    Enhanced DNA photocleavage and binding properties of sapphyrin-polyamine conjugates

  • Author/Authors

    Jonathan L. Sessler، نويسنده , , Andrei Andrievsky، نويسنده , , Petra I. Sansom، نويسنده , , Vladim?r Kr?l، نويسنده , , Brent L. Iverson، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1997
  • Pages
    4
  • From page
    1433
  • To page
    1436
  • Abstract
    The synthesis of several water-soluble sapphyrin derivatives is described. Of these, the sapphyrins 2–4, bearing appended polyamines, exhibit enhanced DNA photocleavage and binding over sapphyrin 1 as determined from pBR322 plasmid cleavage experiments and an ethidium bromide displacement fluorescence assay.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1997
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    788784