Title of article
Potent novel nonsteroidal androgen antagonists with a phthalimide skeleton
Author/Authors
Hiroyuki Miyachi، نويسنده , , Akihiko Azuma، نويسنده , , Takuya Kitamoto، نويسنده , , Kozue Hayashi، نويسنده , , Shigeaki Kato، نويسنده , , Masafumi Koga، نويسنده , , Bunzo Sato، نويسنده , , Yuichi Hashimoto، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
6
From page
1483
To page
1488
Abstract
Anti-androgenic activity of various phthalimide analogs was evaluated based on inhibition of androgen-induced activation of nuclear androgen receptor (CAT assay) and on growth inhibition of the androgen-dependent clonal cell line SC-3. Some compounds showed very potent androgen-antagonistic activity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1997
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788794
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