Author/Authors :
Hiroyuki Miyachi، نويسنده , , Akihiko Azuma، نويسنده , , Takuya Kitamoto، نويسنده , , Kozue Hayashi، نويسنده , , Shigeaki Kato، نويسنده , , Masafumi Koga، نويسنده , , Bunzo Sato، نويسنده , , Yuichi Hashimoto، نويسنده ,
Abstract :
Anti-androgenic activity of various phthalimide analogs was evaluated based on inhibition of androgen-induced activation of nuclear androgen receptor (CAT assay) and on growth inhibition of the androgen-dependent clonal cell line SC-3. Some compounds showed very potent androgen-antagonistic activity.
